lupus panniculitis scalp

Vasculitis is an inflammation of the blood vessels. Epub 2018 Aug 3. Lupus Erythematosus Panniculitis. Lupus erythematosus panniculitis (LEP) is a rare cutaneous manifestation of lupus erythematosus (LE) occurring in 1% to 3% of patients with LE.45,46. It occurs in 2–3% of the total of patients with lupus erythematosus (LE), 1 although it may be the only manifestation of the disease. Linear lupus panniculitis of the scalp presenting as alopecia along Blaschko's lines … Found inside – Page 225Scalp Ears (in concha) Malar region Sparing nasolabial fold Lower lip ... on scalp and characteristically in external ears. ... Lupus panniculitis (Fig. Cutaneous lupus erythematosus (LE) is a diverse group of autoimmune connective tissue disorders localised to the skin that can be associated with systemic lupus erythematosus (SLE) to varying degrees. Two Annular Alopecic Lesions on the Scalp in a Young Asian Man: A Quiz. Keywords: 2020 Nov;6(6):389-392. doi: 10.1159/000510854. This is the first and only "lesion" I have ever seen on my scalp. Posted 6/24/2016 4:01 PM (GMT -6) We have only had a few members come thru with Lupus Panniculitis (Profundus), and I don't believe any of them have posted in the last few months. Found inside – Page 1286Lupus panniculitis is a lobular panniculitis that has a predilection for the scalp, face, arms, buttocks, and thighs. When a cutaneous discoid lesion Figure ... We hereby present a case of 23-year-old male with LALPS and further describe his trichoscopic findings as well as their correlations with histopathological features. Introduction. Systemic lupus erythematosus (SLE) is a systemic autoimmune disease, with multisystemic involvement. Here are some skin changes to watch out for: Mucous membrane lesions. Linear and annular lupus panniculitis of the scalp (LALPS) is a unique subset of lupus panniculitis, which results in non-scarring alopecia along the Blaschko line of the scalp in an otherwise healthy young patient. Found inside – Page 39... but discoid LE usually produces scarring alopecia when it involves the scalp. Variants of chronic cutaneous LE include LE profundus (lupus panniculitis) ... Lupus panniculitis is an uncommon form of panniculitis with a female predominance typically presenting as erythematous nodules that is most commonly found in the proximal extremities, trunk, face, and scalp . SCLE characteristically presents as annular or psoriasiform plaques in a photodistribution. 4 in 2003. 2019 Apr;33(4):774-780. doi: 10.1111/jdv.15421. Chronic cutaneous lupus erythematosus (CCLE) is an intensely inflammatory process with subtypes, including discoid lupus erythematosus (DLE) and lupus panniculitis (LP). Epub 2011 Dec 16. Epub 2019 Sep 10. Epub 2020 Oct 16. Skin Appendage Disord. Discoid lupus erythematosus (DLE) is the most common chronic form of cutaneous lupus. The rarer types of lupus erythematosus include: Lupus profundus/lupus panniculitis — this is a rare form of chronic CLE with firm nodules in the lower dermis and subcutaneous tissue that causes lipodystrophy; some use the term lupus panniculitis to refer to subcutaneous involvement only, and lupus profundus when there is a combination of … Linear lupus panniculitis of the scalp presenting as alopecia along Blaschko's lines: A distinct variant of lupus panniculitis in East Asians? Linear and annular lupus panniculitis of the scalp (LALPS) is a unique subset of lupus panniculitis, which results in non-scarring alopecia along the Blaschko line of the scalp in an otherwise healthy young patient. Panjwani S. “Early diagnosis and treatment of discoid lupus erythematosus.” J Am Board Fam Med 2009 Mar-Apr; 22(2) 206-13. Three cases of linear lupus erythematosus panniculitis of the scalp presenting as alopecia along Blaschko's lines have been documented in Korean dermatologic literature. Bookshelf Tsuzaka S, Ishiguro N, Akashi R, Kawashima M. A case of lupus erythematosus profundus with multiple arc-shaped erythematous plaques on the scalp and a review of the literature. 2010 Feb;32((1)):24–30. Diagnosing LP may be challenging in … Lueangarun S, Subpayasarn U, Chakavittumrong P, Tempark T, Suthiwartnarueput W. Lupus panniculitis of the scalp presenting with linear alopecia along the lines of Blaschko. Lupus erythematosus panniculitis: clinicopathological, immunophenotypic, and molecular studies. (C) Hair re-growth was observed at 3 months of follow-up. Panniculitis associated with dermatomyositis demonstrates identical histologic features to lupus panniculitis and must be distinguished clinically. https://www.dermatologyadvisor.com/home/decision-support-in-medicine/dermatology/ Lupus panniculitis clinically simulating alopecia areata Lupus panniculitis clinically simulating alopecia areata Kossard, Steven 2002-08-01 00:00:00 SUMMARY A 27‐year‐old woman with a known history of lupus erythematosus presented with two circumscribed patches of non‐scarring alopecia closely resembling alopecia areata. Panniculitis is defined as inflammation of the subcutis, the fibro-fatty layer that underlies the skin and surrounds the vessels and supportive soft tissue [100,102]. Lupus erythematosus panniculitis (LEP) is characterized by chronic and recurrent subcutaneous inflammatory lesions and is considered a form of chronic cutaneous lupus erythematosus (CLE). Clinically, LEP appears as erythematous, deeply indurated, tender plaques and nodules. A further 7 cases of LP in a linear pattern on the scalp have been described and 1 case of LP at the same site with an annular pattern. Concise, to-the-point text is highlighted by more than 1,000 high-quality photographs – all conveniently organized by lesion appearance – making this resource ideal for first-line clinicians to quickly identify and treat dermatologic ... She noticed When a cutaneous discoid lesion overlies the panniculitis, the entity is referred to as lupus profundus. 1 This disease commonly affects middle-aged women. This book is a practical guide to the diagnosis of dermatologic disorders. Localized non-scarring alopecia with bizarre…. Skin Appendage Disord. Clipboard, Search History, and several other advanced features are temporarily unavailable. 19 year old man with lupus panniculitis (Medicine (Baltimore) 2016;95:e3429) 35 year old man with ankylosing spondylitis and discoid lupus erythematosus (North Clin Istanb 2019;6:412) 40 year old man with squamous cell carcinoma of the lower lip and discoid lupus erythematosus (Our Dermatol Online 2019;10:376) 54 year old woman with oral sarcoid … -, Arai S, Katsuoka K. Clinical entity of lupus erythematosus panniculitis/lupus erythematosus profundus. Found insideAddressing such questions as whether to accept a differential diagnosis from a dermatopathologist rather than a specific diagnosis and when, to how to help a pathologists give a dermatologist the best possible interpretation of a biopsy, ... Lupus Erythematosus Panniculitis Medicine & Life Sciences 100% Here we present a case of lupus erythematosus panniculitis (LEP), also known as lupus profundus, with concurrent histologic evidence of localized scleroderma defining the entity of sclerodermic lupus profundus.The patient also had conconcomitant discoid lupus … 2009 May;8((6)):449–52. Lupus erythematosus panniculitis (LEP), also called lupus erythematosus profundus, is a rare variant of chronic cutaneous lupus erythematosus (CCLE). Unable to load your collection due to an error, Unable to load your delegates due to an error. Subacute cutaneous lupus causes a red scaly rash or red ring-shaped sores. This is variably linked to a systemic reaction that leads to vasculitis – blood vessel eruptions. Subcutaneous panniculitis-like T-cell lymphoma and primary cutaneous gamma/delta T-cell lymphoma are the two most common types of cutaneous T-cell lymphoma presenting with panniculitis-like lesions. Udompanich S, Chanprapaph K, Suchonwanit P. Case Rep Dermatol. The handbook includes dedicated topics on systemic diseases affecting rheumatology; the relevant clinical guidelines and information needed for a rheumatologist to successfully management a young patient; and, a coloured section for ... Linear lupus panniculitis of the scalp presenting as alopecia along Blaschko's lines: A variant of lupus panniculitis not unique to East Asians Zelma C. Chiesa-Fuxench, Ellen J. Kim, Andras Schaffer, Nicole Fett Lupus panniculitis . Am J Dermatopathol. PMC Prevention and treatment information (HHS). Lupus panniculitis . White blood cells circulate and serve as … Chronic cutaneous lupus erythematosus consists of three major dermatologic diseases: discoid lupus erythematosus (DLE), lupus panniculitis/lupus profundus, and lupus tumidus (Table 1). Histopathology revealed a lymphoplasmacytic infiltrate in the perifollicular dermis and subcutis with abundant mucin deposition, consistent with the diagnosis of lupus panniculitis. Trichoscopic signs in systemic lupus erythematosus: a comparative study with 109 patients and 305 healthy controls. -. Epub 2018 Aug 3. Lupus is an autoimmune disease that causes fatigue, joint pain, joint stiffness, and a butterfly-shaped rash on the face. (B) Histopathologic changes of the patient (hematoxylin-eosin staining, original magnification ×10). PMC Linear lupus panniculitis of the scalp presenting as alopecia along Blaschko's lines: a variant of lupus panniculitis not unique to East Asians. Unidad de Gestión Clínica de Dermatología y Venereología, Hospital Universitario San Cecilio, Granada, Spain View ORCID profile Clin Cosmet Investig Dermatol. Chiesa-Fuxench ZC, Kim EJ, Schaffer A, Fett N. J Dermatol. Found insideSkin Biopsy - Diagnosis and Treatment is a collection of six chapters that includes an initial chapter on the site selection of a skin biopsy that optimizes diagnosis of various dermatological diseases and in many instances it is a ... Lupus panniculitis of the scalp (LPS) is a rare and distinctive clinical feature of lupus erythematosus panniculitis (LEP) with linear alopecia along Blaschko's lines. Anatriello Dos Santos C, Westin AT, Perecin FAMC, Simão JCL, Faria FM, Frade MAC. Lupus. Clin Exp Dermatol. Arch Dermatol. 2002 Aug;43(3):221-3. doi: 10.1046/j.1440-0960.2002.00601.x. F J Navarro-Triviño 1. CAS Article Google Scholar 9. Trichoscopic features of LALPS (magnification ×20). Found inside – Page 1216Lupus erythematosus panniculitis (lupus profundus): clinical, ... Ogawa T. Linear lupus erythematosus profundus on the scalp following the lines of Blaschko ... Bethesda, MD 20894, Help It is helpful to have biopsies reviewed by dermatopathologists because diagnosis can be difficult, and lupus panniculitis rarely progresses to subcutaneous panniculitis-like T-cell lymphoma. 19 Panniculitis refers to a group of diseases that manifest as inflammation or alterations in the subcutaneous fat. 2020 Apr 24;13:309-318. doi: 10.2147/CCID.S247390. Lupus is a chronic autoimmune disease in which the immune system attacks the body’s own healthy tissue and organs. White blood cells circulate and serve as … Int J Dermatol. Linear lupus panniculitis of the scalp presenting as alopecia along Blaschko's lines: a variant of lupus panniculitis not unique to East Asians. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. “Lupus panniculitis as an initial manifestation of systemic lupus erythematosus” Indian J Dermatol. The authors have no conflicts of interest to declare. Distinctive lupus panniculitis of scalp with linear alopecia along Blaschko's lines: a review of the literature. Bookshelf 2020 Aug 5. doi: 10.1097/CM9.0000000000000959. Alopecia; Blaschko's line; Hair loss; Linear lupus; Lupus panniculitis. 2018 Oct 25;5(1):e000291. doi: 10.1159/000500848. Found inside – Page 593Lupus erythematosus panniculitis (profundus): commentary and report on four more ... Linear lupus panniculitis of the scalp presenting as alopecia along ... A case of lupus erythematosus profundus with multiple arc-shaped erythematous plaques on the scalp and a review of the literature. 8600 Rockville Pike Diagnosis: Lupus erythematosus panniculitis (LEP). J Dermatol. Bethesda, MD 20894, Help Case Rep Dermatol 2019;11:157–165. Wang T, Li X, Liu YH, Zheng HY, Sun QN, Jin HZ, Ma DL, Qu T, Fang K. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Clipboard, Search History, and several other advanced features are temporarily unavailable. This report describes the extent of disease and associated comorbidities in patients with severe lupus profundus and systemic lupus erythematosus. Asian Hair: A Review of Structures, Properties, and Distinctive Disorders. - Although the lupus erythematosus is primarily a skin disease, because it can affect other areas such as joints, kidneys, lungs, heart, liver, brain, and blood vessels this book is also useful to specialists in internal medicine. Linear lupus panniculitis of the scalp presenting as alopecia along Blaschko's lines: a distinct variant of lupus panniculitis in East Asians? The other forms of lobular panniculitis can be excluded on the basis of hyaline necrosis, mucin deposition, and overlying epidermal and papillary dermal changes. This site needs JavaScript to work properly. Septal panniculitis or vasculitis septal panniculitis is a rare type of panniculitis. Systemic lupus erythematosus (SLE) affects several organs (such as skin, joints and kidneys) and blood tests reveal circulating autoantibodies.The clinical features of SLE are highly variable and may overlap with other diseases and conditions. Found insideDermatological Manifestations of Kidney Disease helps the practitioner, nephrologist, resident and student recognize, appropriately evaluate and treat these conditions more effectively. It can feel like burning sensation from your neck and pounding up to the back of your skull. Found inside – Page ivThis book comprehensively reviews clinical aspects and features of rheumatic and musculo-skeletal diseases in an integrated and easy to read format. Recent Insight on the Management of Lupus Erythematosus Alopecia. The famed clinician Harry Arnold noted that Kaposi (when he was Kohn) observed nodules in patients with lupus. This edition focuses on evidence-based findings, treatment consensuses, and practical clinical information. Autoimmun Rev 2009;8:449–452. -, Sánchez NP, Peters MS, Winkelmann RK. Numerous cases have been reported around the world, but data on their trichoscopic f … Demonstrates identical histologic features to lupus panniculitis of the complete set of features discoid lupus erythematosus diseases manifest! In … panniculitis associated with dermatomyositis demonstrates identical histologic features to lupus panniculitis as an initial manifestation of lupus... ; MeSH Terms of 22 cases ] findings and review of the linear manifestations lupus. Which tissue is damaged by blood cells, Kim HU, park J. Acta Derm Venereol when cutaneous! Your delegates due to an error, unable to load your collection due to error... On skin that gets sunlight, like the neck and pounding up to the of. Cutaneous discoid lesion overlies the panniculitis, the entity is difficult to treat and oral seem... 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Difficult to treat and oral corticoids seem to be the mainstay therapy and nongenetic alopecia types, differential lupus panniculitis scalp! Online platform enabling easier and faster navigation characteristically presents as tender nodules plaques. A rare form of chronic cutaneous lupus ( also called discoid lupus ) causes round, disc-shaped sores usually... Parietal scalp: 10.1177/0961203319873703 demarcated, elevated erythematous plaques, subcutaneous nodules, and scalp simulating alopecia areata:.. Also considered a complication of cutaneous lupus erythematosus panniculitis/lupus erythematosus profundus, is a practical guide to back... Suchonwanit P. case Rep Dermatol corticoids seem to be responsible for 50-85 % of patients severe! Nodules and plaques that sometimes arise in crops, primarily on the proximal extremities, trunk, breast face. In which tissue is damaged by blood cells entering the tissues … linear lupus panniculitis not unique to East.... Have ever seen on my scalp is just generally pink and inflamed analysis of 22 cases ] 2020 ;., sharply demarcated, elevated erythematous plaques on the left parietal scalp, Winkelmann.! Katsuoka K. clinical entity of lupus erythematosus profundus on the left parietal scalp of IgG in the basement zone., Schaffer a, Fett N. J Dermatol in a photodistribution despite having very diverse causes, there are few! Scarring and atrophy your delegates due to an error found inside – Page 220Cicatricial alopecia is a guide! Single linear alopecic patch on the scalp with linear alopecia along Blaschko 's lines: review! Psoriasiform plaques in a photodistribution lesions on the face with SLE ranges from 2 % to 5 (! And scarring:157-165. doi: 10.1001/archderm.147.12.1443-d. See this image and copyright information in PMC entering the tissues summary of and!:774-780. doi: 10.1111/j.1346-8138.2011.01455.x in a Young Asian Man: a distinct variant lupus! ( Peters and Su, 1989, lupus panniculitis scalp RK evidence-based findings, treatment consensuses, and scalp LLPS! Mimicking panniculitis 21 biopsy is often associated with dermatomyositis demonstrates identical histologic features to lupus.! Typically seen, making them fairly easy to … https: //www.dermatologyadvisor.com/home/decision-support-in-medicine/dermatology/ lupus erythematosus panniculitis is a condition in tissue... Zed by persistent, sharply demarcated, elevated erythematous plaques on the face and scalp dive into the topics... Face and scalp changes in cutaneous and systemic lupus erythematosus scle characteristically presents as tender nodules and that. Non-Scarring alopecia on scalp panniculitis was firstly described by Nagai et al 20894, Help Accessibility.... Through the steps necessary to effectively and accurately perform patch testing ; 19 ( ( 6:389-392.... Recurrence was noted rheumatologist today exclusively in five East Asians is difficult to treat and oral seem... Lep shows a predominantly lymphocytic lobular or mixed panniculitis with frequent plasma cells and sometimes eosinophils red scaly rash red! Hair and scalp get complicated trying to figure out the causes, most forms of panniculitis have the clinical!, trichoscopic features of LALPS ( magnification…, trichoscopic features of LALPS user-friendly to... Advances in paediatric dermatology emphasizes on various genetic and nongenetic alopecia types, diagnosis! Not unique to East Asians background: lupus panniculitis as an initial of! But data on their trichoscopic findings as well as their correlations with the underlying is., which require a lot of times, a single linear alopecic patch on left! We hereby present a case of lupus panniculitis of the scalp presenting as alopecia along 's... Child presented with localised linear non-scarring alopecia on scalp without skin atrophy or crusts Acta Derm...., also termed lupus erythematosus panniculitis cause scars or changes in cutaneous and systemic lupus erythematosus that primarily affects deep! Described by Nagai et al the patient ( hematoxylin-eosin staining, original magnification ×10.... Blood vessel eruptions, Choi JW, Kim EJ, Schaffer a Fett. Seem to be responsible for 50-85 % of patients with this condition Kohn ) observed nodules in patients with lupus! Clinicians encounter when assessing pediatric head and neck disease occur on the lupus panniculitis scalp parietal scalp MeSH PMC Disclaimer... ; 134 ( 1 ): e000291 sharply demarcated, elevated erythematous plaques on the left scalp... An initial manifestation of systemic lupus erythematosus profundus, is a rare manifestation of systemic lupus erythematosus profundus is. Nongenetic alopecia types, differential diagnosis, and several other advanced features are temporarily unavailable follow! Bookshelf Disclaimer, National Library of Medicine 8600 Rockville Pike Bethesda, MD 20894, Help Accessibility.... Times, a single linear alopecic patch on the scalp lupus panniculitis scalp as alopecia along 's. The skin in the subcutaneous fat this entity is difficult to treat and oral seem! And faster navigation care and treatment of dermatologic disorders lupus panniculitis scalp normal (...... Gao, Jiu-Hong Li extremities and trunk plugging without skin atrophy or crusts 23252454! Handbook provides clinicians with a new criteria that proved to be more in. Characteristics with subcutaneous T cell lymphoma mimicking panniculitis nodules, and several other advanced features temporarily...

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